Functional foods with dipeptidyl peptidase?4 inhibitory potential and management of type 2 diabetes: A review

The global high prevalence of diabetes mellitus has resulted into the development several oral hypoglycemic agents. However, these drugs have limited efficacy and harmful side effects, which call for search alternatives from natural sources. inhibition dipeptidyl peptidase-4 (DPP-4) activity increases level glucagon-like peptide-1 glucose-dependent insulinotropic polypeptide, in turn reduces hyperglycemia by activating insulin secretion inhibiting glucagon secretion. Some studies reported vitro DPP-4 inhibitory potential functional foods, but there is no repository information on reports. This article an attempt to present concise form, reports foods with potentials vitro. will guide use as well antidiabetic drug development.